ADRBK1 polyclonal antibody
产品名称： ADRBK1 polyclonal antibody
英文名称： ADRBK1 polyclonal antibody
产品编号： PAB6974
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of ADRBK1.
- Immunogen:
- A synthetic peptide corresponding to human ADRBK1.
- Sequence:
- C-RDAYREAQQLVQR
- Host:
- Goat
- Theoretical MW (kDa):
- 79.7
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure.
Iaccarino G, Barbato E, Cipolletta E, De Amicis V, Margulies KB, Leosco D, Trimarco B, Koch WJ.Eur Heart J. 2005 Sep;26(17):1752-8. Epub 2005 Jul 29.
- Entrez GeneID:
- 156
- Protein Accession#:
- NP_001610.1
- Gene Name:
- ADRBK1
- Gene Alias:
- BARK1,BETA-ARK1,FLJ16718,GRK2
- Gene Description:
- adrenergic, beta, receptor kinase 1
- Omim ID:
- 109635
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq
- Other Designations:
- beta adrenergic receptor kinase 1
- Gene Pathway