TIMP1 polyclonal antibody
产品名称： TIMP1 polyclonal antibody
英文名称： TIMP1 polyclonal antibody
产品编号： PAB24555
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of TIMP1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 129-143 at internal region of human TIMP1.
- Sequence:
- C-NSLSLAQRRGFTKTY
- Host:
- Goat
- Theoretical MW (kDa):
- 24
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Storage Buffer:
- In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 7076
- Protein Accession#:
- NP_003245.1
- Gene Name:
- TIMP1
- Gene Alias:
- CLGI,EPA,EPO,FLJ90373,HCI,TIMP
- Gene Description:
- TIMP metallopeptidase inhibitor 1
- Omim ID:
- 305370
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq
- Other Designations:
- OTTHUMP00000023214,erythroid potentiating activity,fibroblast collagenase inhibitor,tissue inhibitor of metalloproteinase 1
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