LRRK2 polyclonal antibody
产品名称： LRRK2 polyclonal antibody
英文名称： LRRK2 polyclonal antibody
产品编号： PAB12393
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to amino acids 2480-2527 of human LRRK2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Pig, Primates, Rat
- Form:
- Liquid
- Storage Buffer:
- In Tris-glycine (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ.Neuroscience. 2007 Jul 29;147(4):1047-58. Epub 2007 Jul 3.
- Entrez GeneID:
- 120892
- Protein Accession#:
- Q5S007
- Gene Name:
- LRRK2
- Gene Alias:
- AURA17,DARDARIN,PARK8,RIPK7,ROCO2
- Gene Description:
- leucine-rich repeat kinase 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
- Other Designations:
- Parkinson disease (autosomal dominant) 8,augmented in rheumatoid arthritis 17
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aphasia, Primary Progressive
- Chromosome Aberrations
- Cognition
- Cognition Disorders
- Crohn Disease
- Dementia
- Disease Progression
- Dominance, Cerebral
- Dyskinesias
- Dystonic Disorders
- Essential Tremor
- Essential tremor
- Functional Laterality
- Gaucher disease
- Genetic Predisposition to Disease
- Heredodegenerative Disorders, Nervous System
- Huntington Disease